Both Manchester City and Manchester United are out of the Europa League after failing to progress from their round of 16 ties.
City crashed out despite staging a rousing second half fightback against Sporting to pick up a 3-2 win on the night.
The away goals rule put paid to the Blues' dreams, with the two-legged tie ending 3-3 on aggregate.
Goals from Matias Fernandez and Ricky van Wolfswinkel helped to edge Sporting through and ensured that City joined arch-rivals United in bowing out.
Two goals from Sergio Aguero and a penalty from Mario Balotelli offered City hope of turning a remarkable game on its head, but it was not to be for Roberto Mancini's side despite Joe Hart going close with a very late header.
Wayne Rooney's 27th goal of the season proved to be little consolation for United as they lost 2-1 on the night and 5-3 on aggregate against Athletic Bilbao.
Bilbao took the lead on the night with a stunning goal after 23 minutes as Fernando Llorente demonstrated perfect technique to strike a first-time volley into the bottom corner from a long ball over the top of the United defence.
Further chances came and went for the home side before Oscar de Marcos made it 2-0 in the 65th minute with a shot from 12 yards that deflected past David de Gea.
Wayne Rooney pulled a goal back with a tremendous curling effort time to give United a lifeline and set up a more interesting finale, but Bilbao held firm to advance to the quarter-finals.