Andy Roddick was unceremoniously dumped out of the Regions Morgan Keegan Championships in the first round by Xavier Malisse.
The Belgian upset the second seed as he prevailed 7-6 (10-8) 7-5 to set up a second-round clash with Benjamin Becker. The German beat Dudi Sela 6-4 6-1.
Alex Bogomolov Jr was another seed eliminated in Memphis when he was beaten 1-6 6-4 7-6 (7-5) by Malisse's fellow Belgian Olivier Rochus, while sixth-seed Julian Benneteau was beaten in successive tie-breaks by Philipp Petzschner.
But there were straight-sets wins for Radek Stepanek, Milos Raonic and Kevin Anderson - the third, fourth and seventh seeds - against Bobby Reynolds, Ernests Gulbis and Robby Ginepri respectively.
Jurgen Melzer won a hard-fought match against Denis Istomin 6-7 (2-7) 6-3 7-6 (7-4) and Pole Lukasz Kubot beat Jesse Levine 7-6 (7-2) 6-4.
