Scotland's Jamie Baker set up a second-round clash with Jo-Wilfried Tsonga after beating England's Oliver Golding in straight sets at the AEGON Championships.
Resuming after a rain delay on day two at Queen's, world no. 482 Golding defied the odds to keep pace with Baker in the first set.
British number three Baker came in to his own during the tie-break, however, which he won 7-1.
Golding then had an argument with the umpire following a dubious line call at the start of the second set and went on to trail 0-4.
He rallied momentarily, but Baker eased home to record a 7-6 (7/1) 6-3 win.
Baker, ranked 203 in the world, has played Tsonga once before in Lanzarote five years ago when the world number five won easily in straight sets.
Four years ago at the age of 21 Baker was in intensive care for three days in Florida after being diagnosed with the deadly blood disease idiopathic thrombocytopenic purpura (ITP).
The British number three was told he was unlikely to play again, but he made a full recovery and now looks set to climb in to the top 200, something which he thinks is down to the resilience he has built since being struck down by ITP.
"Recovering from that was obviously bigger than any tennis match or anything I'll ever do on the tennis court," he said.
"Everything else at the time paled in to insignificance.
"When I came back I realised how tough it was going to be to actually get my fitness back.
"I was on the court, but my body had been knocked to the floor basically.
"But it's not something that I think about now. In fact, I see it actually as part of why I'm at my highest ranking now.
"I have had to be pretty strong to get through and come back from something like that."
Baker's recovery from the illness has been hit by ankle and abdominal muscle injuries, but he is now full of confidence having beaten English prodigy Golding and being handed a wild card in to Wimbledon.
But he is under no illusions as to how hard it will be to defeat Tsonga, who reached the final here last summer before losing to Andy Murray.
When asked what he would consider being a good week for him at Queen's, Baker said: "Have you seen who I play next?!
"I was watching him play Djokovic last week.
"I said to the person I was watching with: 'I wonder what I'd actually do if I played one of these guys?'
"I guess I'm going to have to think about that tonight now!"
Baker's one meeting with Tsonga ended in a straight sets defeat to the Frenchman in Lanzarote five years ago.
"Individually this is definitely my biggest match," he said. "He's unbelievable athlete."